A refined base-pair editor limits unintended neighboring DNA edits while maintaining strong correction of disease-causing ...

Manipulating “thresholds” with mitochondrial gene editing tools. By focusing on the genetic roots of neurodegenerative diseases, mitochondrial DNA editing represents a shift in therapeutic strategies.

For decades, scientists have studied how to control DNA—the molecule that holds the instructions for all life. One of the most powerful tools to emerge from that effort was CRISPR, a system adapted ...

Mitochondrial DNA (mtDNA) editing has emerged as a revolutionary approach in the fight against neurodegenerative diseases (NDDs). As these diseases continue to impose a significant global health ...

Scientists from the Helmholtz Institute for RNA-based Infection Research (HIRI) and collaborating institutions have developed a DNA-editing method that introduces small chemical modifications at ...

New research dramatically expands the number of naturally occurring versions of CRISPR-associated transposons (CASTs), giving researchers a wealth of potential new tools for large-scale gene editing.

You may have seen it in the news recently: a baby in Pennsylvania with a rare genetic disorder was healed with a personalized treatment that repaired his specific genetic mutation. The treatment was ...

Hi. I’m Art Caplan. I'm at the Division of Medical Ethics at NYU Grossman School of Medicine. Some leading organizations in the field of cell and gene therapies recently issued a call for a 10-year ...

Dr Constantinos Patinios, a researcher at the EMBL Partnership Institute at Vilnius University Life Sciences Center (VU LSC), ...