Researchers from Rice University and St. Jude Children’s Research Hospital in Memphis, Tennessee, took a close look at one of the ways cells repair broken strands of DNA and discovered details that ...
A major advance in cell biology has revealed how our cells safeguard their genetic material during one of the most vulnerable moments in their life cycle. The study identifies a specific protein ...
Researchers found that losing a second protein, FIGNL1, allows cancer cells missing BRCA2 to restore DNA repair by reloading RAD51 onto broken DNA strands. Normally, BRCA2 helps place RAD51 at DNA ...
DNA repair proteins act like the body’s editors, constantly finding and reversing damage to our genetic code. Researchers have long struggled to understand how cancer cells hijack one of these ...
The mechanisms that repair mitochondrial DNA aren’t well characterized. © Getty Images\iStockphoto Researchers have uncovered DNA repair machinery active in ...
Not all DNA looks like the familiar double helix. Sometimes, parts of our genetic code fold into unusual shapes under certain conditions. One such structure known as a G-quadruplex (G4) looks like a ...
U.S. Fast Track designation of ART6043 underpinned by promising clinical data to date and high unmet need in gBRCA-mutated HER2-negative breast cancerArtios is launching a global randomized Phase 2 ...
Scientists have discovered that naked mole-rats, known for their remarkable longevity and resistance to age-related diseases, possess a unique DNA repair protein. This modified protein enhances ...