Mutations are changes in the molecular "letters" that make up the DNA code, the blueprint for all living cells. Some of these changes can have little effect, but others can lead to diseases, including ...

New research from a team of genome scientists and DNA damage response experts breaks new ground in understanding the function of a protein currently limited in clinical trials for cancer treatments.

A new long-read sequencing technique has helped researchers investigate how DNA mutations arise in a variety of contexts. A collaboration of researchers led by NYU Langone Health and NYU Grossman ...

DNA損傷応答（DDR）はゲノムの恒常性維持において非常に重要な役割を担っている。 DNA損傷やDDR活性化が心不全を起こした心臓で観察されることは報告されているが、どのような種類のDNA損傷が起こっており、心不全の発症機序にどのような役割を果たして ...

New research from a team of genome scientists and DNA damage response experts breaks new ground in understanding the function of a protein currently limited in clinical trials for cancer treatments.

DNA is constantly damaged by radiation, chemicals, and our metabolism. Cells have developed sophisticated ways to detect and repair DNA damage, including the Fanconi Anaemia pathway which repairs DNA ...

Getting DNA into a living cell sounds simple, until you remember the cell’s outer membrane acts like a guarded wall. DNA strands carry a negative charge, and they do not cross that wall easily.

Researchers from Tokyo Metropolitan University have created a new molecule which carries DNA into biological cells, to treat or vaccinate against illnesses. Many existing options rely on molecules ...