The tiny shell protecting the HIV virus resembles a slightly rounded ice cream cone, but there is nothing sweet about it.

The rate of HIV infection continues to climb globally. Around 40 million people live with HIV-1, the most common HIV strain. While symptoms can now be better managed with lifelong treatment, there is ...

The rate of HIV infection continues to climb globally. Around 40 million people live with HIV-1, the most common HIV strain. While symptoms can now be better managed with lifelong treatment, there is ...

Researchers mapped HIV-1’s translation strategy, revealing RNA elements like uORFs, iORFs, and an intricate frameshift site structure that regulate viral protein synthesis. These findings highlight ...

It was previously demonstrated that the HIV-1 integrase (IN)-interacting host factor INI1/SMARCB1 binds to HIV-1 IN through its Rpt1 domain of INI1 (INI1-Rpt1) and plays a key role in assembly and ...

I see that ViroLogic now offers information on the replicative capacity of patient virus, alongside information on its genotypic and phenotypic resistance profile. How should we use this information ...

On the left is integrase in its “intasome” structure of four identical four-part complexes (pink) that connect to create one 16-part complex that locks around viral DNA (blue). On the right is ...

Can HIV cure be achieved in children? Children with HIV face a lifetime of antiretroviral therapy (ART) to suppress HIV replication. While this is one outlook, an HIV cure in children would re-write ...