A team led by researchers from Tianjin University (P.R. China) has solved the structure of the Zika virus helicase, which is a key target for antiviral development. The research is published in ...

NEW YORK, February 26, 2019 - DNA replication is a complex process in which a helicase ring separates the DNA molecule's two entwined and encoded strands, allowing each to precisely reproduce its ...

The process by which genes are duplicated is mysterious and complex, involving a cast of characters with diverse talents and the ability to play well with others in extremely close quarters. A key ...

This movie shows the helicase protein complex from all angles, and reveals how its shape changes back and forth between two forms. The research team hypothesizes that the rocking action of this ...

With an eye toward understanding DNA replication, researchers have learned how a helicase enzyme works to actually unzip the two strands of DNA. With an eye toward understanding DNA replication, ...

In a recent study posted to the bioRxiv* preprint server, researchers visualized the mechanism of action and inhibition of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) non-structural ...

Helicases are enzymes that unwind DNA and RNA. They're central to cellular life, implicated in a number of cancers and infections - and, alas, extraordinarily difficult to target with drugs. Now, new ...