産業技術総合研究所

Structure and function of the histone chaperone CIA/ASF1 complexed with histones H3 and H4

ヒストンシャペロンCIA/Asf1とヒストンH3, H4からなる複合体の構造と機能 Structure and function of the histone chaperone CIA/ASF1 complexed ...
産業技術総合研究所

Relationship between the structure of SET/TAF-Iβ/INHAT and its histone chaperone activity

DNAは核の中で単独に存在している訳ではなく、通常ヒストンと呼ばれる蛋白質に巻きついており、必要な時以外はむやみにその遺伝情報が読まれないようになっている。この構造をヌクレオソーム構造という。逆にDNA上にある遺伝情報が必要になると ...
Fred Hutch

Snapping the histone CENP-A in place for high-fidelity cell division requires supervision

Human disease including cancer arises from disfunction of essential processes within a cell. One essential cellular process is the copying of the genomic DNA—the road map of cells—followed by ...
EurekAlert!

Chromosomes and spindles in mature oocytes are stabilized by the histone modification

A picture of a mouse MII stage eggs with the location of chromosomes (green) and the distribution of the histone modification H3K4me3 (purple). The team confirmed that H3K4me3 was significantly ...
Medical Xpress

Amino Acid, Peptide, or Protein:

Imagine if we could inhale scents that delay the onset of cancer, inflammation, or neurodegenerative disease. Researchers at the University of California, Riverside, are poised to bring this ...