Proteins are the infinitely varied chemicals that make cells work, and science has a pretty good idea how they are made. But a critical aspect underlying the machinery of protein manufacture has long ...

This model of the nucleus with nucleolus (pink) shows how ribosomal DNA is correctly repaired in young cells. In old cells with enlarged nucleolus, however, DNA repair is inaccurate leading to faster ...

Keeping nucleoli small prevents DNA instability and cellular aging, akin to anti-aging effects like calorie restriction Nucleolar expansion marks a tipping point in aging, acting as a "mortality meter ...

The secret to cellular youth may depend on keeping the nucleolus -- a condensed structure inside the nucleus of a cell -- small, according to nvestigators. The findings were elucidated in yeast, a ...

Deep within the intricate world of cellular biology, scientists at Weill Cornell Medicine have made a remarkable discovery about aging that could transform our understanding of human longevity. Their ...

A team led by Princeton University researchers has developed a tool to peer inside the nucleolus, the cellular compartment responsible for the earliest steps in protein manufacture. This system opens ...

Deep within the nucleus of every cell lies a structure smaller than a pinpoint that may hold the secret to aging. Scientists at Weill Cornell Medicine have discovered that the nucleolus, long known ...

RNA, or ribonucleic acid, is a short-lived molecule copied from DNA that enables cells to use genetic information. Specific DNA sequences are copied into RNA, which then delivers these instructions to ...

Research at the University of Jyväskylä (Finland) reveals that autonomous parvoviruses, such as canine parvovirus, are highly capable of affecting the internal balance of the nucleolus. The results ...