Gene expression is linked to RNA transcription, which cannot happen without RNA polymerase. However, this is where the similarities between prokaryote and eukaryote expression end. Central to the ...

Scientists at IOCB Prague are uncovering new details of gene transcription. They have identified a previously unknown molecular mechanism by which the transcription of genetic information from ...

理化学研究所（理研）生命機能科学研究センター 先端NMR開発・応用研究チームの大山 貴子 研究員、石井 佳誉 チームリーダー（東京工業大学 生命理工学院 生命理工学系 教授）らの研究チームは、SARS-CoV-2のゲノム転写開始に関与する3′非翻訳領域[1] で ...

理化学研究所（理研）生命医科学研究センタートランスクリプトーム研究チームのアレッサンドロ・ボネッティ客員研究員、ピエロ・カルニンチチームリーダーらの研究チームは、細胞核内のRNAとゲノムDNA（クロマチン[1] ）の相互作用をゲノム全体で調べる ...

From vaccines and diagnostics to emerging gene-based therapies, RNA molecules are now central to modern medicine. But as ...

直鎖状RNAよりも安定な環状RNAは、RNA治療の新たな扉を開くかもしれない。 RNAワクチンは、新型コロナウイルス感染症（COVID-19）パンデミックに立ち向かったヒーローだった。新薬としては史上最高の売上高を記録し、その開発に対して2023年のノーベル生理学 ...

Inside every cell, thousands of molecular signals collide, overlap, and compensate, obscuring the true drivers of gene expression. Scientists have now developed a way to silence that cellular noise, ...

When a gene is active, there is cellular machinery that transcribes the sequence of that gene from DNA into messenger RNA. This is a fundamental cellular process that is essential to the proper ...

A proposed function of TADs is to contribute to gene regulation by promoting chromatin interactions within a TAD and by suppressing interactions between TADs. Here, we directly probe the ...

Professor Norikazu Ichihashi and his colleagues at the University of Tokyo have successfully induced gene expression from a DNA, characteristic of all life, and evolution through continuous ...