Figure 1: An illustration showing RNA polymerase II (silver structure) transcribing DNA (yellow and orange helix) into messenger RNA. RIKEN researchers have conducted a structural study of the ...
Drug developers & researchers can now leverage the CleanScribe enzyme to reduce dsRNA formation by up to 85% in mRNA synthesis without compromising mRNA yield, capping efficiency, or integrity ...
Morning Overview on MSN
RNA strand that nearly self-replicates could unlock life’s origin
A 45-nucleotide strand of RNA can now synthesize both its mirror-image complement and a copy of itself, bringing scientists ...
Researchers at the MRC Laboratory of Molecular Biology in Cambridge have discovered a ribozyme that is shockingly small, yet ...
SAN DIEGO--(BUSINESS WIRE)--TriLink BioTechnologies and Alphazyme, both part of Maravai LifeSciences, have collaborated to launch CleanScribe™ RNA Polymerase, a novel enzyme that reduces ...
Inside every cell, thousands of molecular signals collide, overlap, and compensate, obscuring the true drivers of gene expression. Scientists have now developed a way to silence that cellular noise, ...
Researchers developed C28, an engineered polymerase that efficiently synthesizes RNA at near-natural speeds with high accuracy. Created through directed evolution, the enzyme also performs reverse ...
Morning Overview on MSN
Self-building RNA strand may expose how life on Earth truly began
Two separate laboratory breakthroughs have produced RNA molecules that can build copies of themselves or assemble functional structures without any help from proteins or DNA. These results offer the ...
Researchers identified how the poxvirus protein VITF-3 forms a molecular ring that clamps onto DNA with viral RNA polymerase, bending it by 90 degrees to initiate gene copying.
A strand of RNA just 45 nucleotides long has been discovered to perform two key reactions required for self-replication. The ...
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