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The life cycle of a protein

A protein’s life is anything but simple. Discover how transcription, translation, folding, modification, and degradation work together to preserve proteome integrity.
Mitochondria possess their own mRNA translation system, mediated by specialized mitoribosomes. Dysregulation of mitochondrial translation disrupts metabolic homeostasis and is linked to various ...
New findings reveal how the gene HNRNPU coordinates several fundamental molecular processes during the earliest stages of human brain development.
tRNAs have a distinct cloverleaf secondary structure and an L-shaped tertiary structure. The cloverleaf structure is formed by the folding of the single-stranded tRNA molecule, which is typically ...
In a new study, published in Cell, researchers describe a newfound mechanism for creating proteins in a giant DNA virus, comparable to a mechanism in eukaryotic cells. The finding challenges the dogma ...