A cancer drug class best known for attacking tumors may also help your immune system remember them better. Researchers at ...

One promising strategy to remuscularize the injured heart is the direct cardiac reprogramming of heart fibroblast cells into cardiomyocytes. Researchers have identified TBX20 as the key missing ...

Researchers have identified key factors that promote the reprogramming of human stem cells to the naïve state, which can be used to model the earliest stages of development. This new knowledge will ...

Cellular reprogramming, when the identity and function of a cell changes, results in the cell acquiring embryonic stem cell pluripotency. This process requires gene expression patterns changes, ...

In summary, macrophages secrete IFN-β, activating the IFN-β-IFNAR-p-STAT1 axis in MICFs, leading to increased secretion of CCL2/7/12 chemokines and subsequent recruitment of more IFN-β-secreting ...

Research from the Babraham Institute has developed a method to ‘time jump’ human skin cells by 30 years, turning back the ageing clock for cells without losing their specialised function. Work by ...

Researchers from Monash University in Melbourne and The University of Western Australia have demonstrated how a reprogramming method imitates embryonic epigenetic reset. Transient naive treatment (TNT ...

A mature cell of one type can be turned into a mature cell of another type without the cell having to pass through an earlier stage of development. This is called direct reprogramming, a reliable but ...

Bengaluru: Indian Institute of Science (IISc) researchers have uncovered new details about how genes are expressed during the reprogramming of adult cells into induced pluripotent stem cells (iPSCs).

The lab of Filippo Veglia, Ph.D., at The Wistar Institute has discovered a previously unknown mechanism for how aggressive brain cancers reprogram immune system cells from fighting cancer to enabling ...