Neurons have a "hibernation mode." Scientists discover how brain cells use RNA tentacles to lock their protein factories together to survive when energy is low.

Ribosomes, the cell's protein-making factories, consume large amounts of energy as they build the proteins that keep cells alive and functioning. When cells experience stress—such as lack of nutrients ...

Ribosomal subunit assembly and biogenesis constitute a fundamental process vital for cellular protein synthesis across all domains of life. This complex, multi-step pathway involves the transcription ...

Ribosomal RNA (rRNA) is a type of molecule and a key building block of the ribosome, the cell's protein-making machinery. rRNA accounts for much of the RNA in a cell, and it's crucial for life. It's ...

Under stress, animal cells pair inactive ribosomes into RNA-linked disomes. A ribosomal RNA “kissing loop” joins them, protecting ribosomes and reducing protein synthesis to conserve energy.<br /> ...

< 3D model of two rat hippocampal ribosomes interacting in a hibernating dimer via an RNA expansion se ... Copyright: Max Planck Institute for Brain Research, 3D models: Oliver Döll.

Ribosomal RNA (rRNA) is a type of molecule and a key building block of the ribosome, the cell’s protein-making machinery. rRNA accounts for much of the RNA in a cell, and it’s crucial for life. “It’s ...

This project aims to unveil physiological roles of RNA modifications associated with fundamental biological processes. We search for novel RNA modifications from human cells and other organisms, and ...

How does a cell know when it’s been damaged? A molecular alarm, set off by mutated RNA and colliding ribosomes, signals danger. When the sun shines on your skin, what does it hit? When it causes a ...

Oceans churned with lava. Air filled thick with smoke. Asteroids stormed down incessantly. Life during the Hadean Eon four billion years ago was a struggle, and yet that was when it began. 1,2 With no ...