The modulation of RNA splicing by small molecules has emerged as a promising strategy for treating pathogenic infections, human genetic diseases, and cancer; however, the principles by which splicing ...
RNA splicing is a post-transcriptional modification process that occurs in eukaryotic cells. When a gene is transcribed, the initial RNA product is called pre-mRNA, which contains both coding regions ...
RNA-based vaccines were the heroes of the COVID-19 pandemic. They set records for the highest-grossing drug launches in history, and their development was recognized in this year’s Nobel Prize in ...
－スプライソスタチンAの強い抗がん活性の解明に迫る－ 理化学研究所（理研）環境資源科学研究センターケミカルゲノミクス研究グループの吉田稔グループディレクター、芳本玲特別研究員（研究当時）、チピ・シュレスタ・ジャガット特別研究員 ...
FUSは転写、選択的スプライシングおよびmRNAの輸送を調節するRNA結合タンパク質である。FUSの異常が家族性および孤発性ALS ...
－心筋症の臨床的意義不明変異のメカニズム解明に貢献－ 理化学研究所（理研）生命医科学研究センター循環器ゲノミクス・インフォマティクス研究チームの伊藤薫チームリーダーらが参加する国際共同研究グループは、難病である特発性拡張型心筋症（DCM ...
RNA is a central biological macromolecule, now widely harnessed in medicine and nanotechnology. Like proteins, RNA function often depends on its precise three-dimensional structure. A recent study ...
RNA is a central biological macromolecule, now widely harnessed in medicine and nanotechnology. Like proteins, RNA function often depends on its precise three-dimensional structure. A recent study ...
In the present context of successful mRNA drugs, the further synthesis of linear mRNA into circular RNA (circRNA) through end-to-end connections to enhance mRNA stability and prolong protein ...
一部の結果でアクセス不可の可能性があるため、非表示になっています。
アクセス不可の結果を表示する