RNA interference is an effective mechanism for gene silencing whereby double-stranded RNA triggers the cleavage and subsequent degradation of homologous transcript sequences. In this evolutionarily ...
Gregory Hannon, Ph.D., Howard Hughes Medical Institute investigator at Cold Spring Harbor Laboratory, and Stephen Elledge, Ph.D., pioneers in the construction of short hairpin RNA interference (shRNAi ...
Over the last decade, RNAi-based loss-of-function screens have proven to be an effective tool to identify essential genes and critical genetic drivers for a host of responses as well as potential drug ...
Sigma-Aldrich has announced that it is working together with the premier scientific journal Cell to offer the article on High Content Viral Library Screens to a wider audience. Written by principal ...