With a new study in the journal Cell, researchers at Stanford University and Stockholm University have contributed to increased knowledge about gene regulation in human cells. How genes are turned on ...

Inside every cell, thousands of molecular signals collide, overlap, and compensate, obscuring the true drivers of gene expression. Scientists have now developed a way to silence that cellular noise, ...

Study in Genes & Development has shown that blocking the transcriptional regulator p300 forces tumour cells into lethal protein stress, re-sensitising chemotherapy-resistant cancers without an ...

Researchers at Osaka University have identified two transcription factors that contribute to the development of gut-resident memory T cells associated with Crohn’s disease, a chronic inflammatory ...

Cells fine-tune gene expression in response to cellular stress, a process critical for tumor progression that leads to cancer. However, elucidating mechanisms governing stress-responsive transcription ...

Two new lines of brain research are testing whether aging cells can be nudged into working more like young ones. In one study ...

A genetic mutation that fuses two genes drives several different cancer types by forming networks of protein interactions that alter gene expression in cells, a study by UT Southwestern Medical Center ...