Researchers showed that LGP2 binds viral RNA ends and recruits MDA5 molecules to form filament clusters that activate ...
This study sheds light on how two well-known proteins work together to trigger an immune signaling cascade in the presence of viral RNA.
To solve a problem, scientists first need to see it clearly. Whether it’s a virus slipping past the immune system or plaques forming in the brain, visualization is the first step toward finding ...
“Our analyses show that the historical [human Rhinovirus] A genome represents an extinct lineage closely related to HRV A19 ...
Mammalian immunity has long been thought to rely solely on proteins and specialized immune cells. However, a newly proposed concept—RNA immunity—is reshaping this perspective. In a recent publication ...
Drugs made of mRNA have the potential to transform medicine—if only they could get into cells in one piece. Now, University ...
Herpes simplex virus type 1 (HSV-1) infection dramatically remodels the host cell's nuclear structures. Infection leads to the formation of viral replication compartments and to chromatin ...
A new method to detect ribonucleic acid (RNA) without needing any complex lab procedures or heating equipment has been developed by researchers at UConn Health. Published in Nature Communications, ...
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Viral RNA modifications trigger celiac inflammation
An EHU study indicates that a drug already approved for use in humans could help to reduce the inflammation associated with celiac disease. The research, conducted by the FunImmune group, shows that ...
理化学研究所(理研)生命医科学研究センタートランスクリプトーム研究チームのアレッサンドロ・ボネッティ客員研究員、ピエロ・カルニンチチームリーダーらの研究チームは、細胞核内のRNAとゲノムDNA(クロマチン[1] )の相互作用をゲノム全体で調べる ...
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