Researchers showed that LGP2 binds viral RNA ends and recruits MDA5 molecules to form filament clusters that activate ...
This study sheds light on how two well-known proteins work together to trigger an immune signaling cascade in the presence of viral RNA.
To solve a problem, scientists first need to see it clearly. Whether it’s a virus slipping past the immune system or plaques forming in the brain, visualization is the first step toward finding ...
“Our analyses show that the historical [human Rhinovirus] A genome represents an extinct lineage closely related to HRV A19 ...
Mammalian immunity has long been thought to rely solely on proteins and specialized immune cells. However, a newly proposed concept—RNA immunity—is reshaping this perspective. In a recent publication ...
Drugs made of mRNA have the potential to transform medicine—if only they could get into cells in one piece. Now, University ...
Herpes simplex virus type 1 (HSV-1) infection dramatically remodels the host cell's nuclear structures. Infection leads to the formation of viral replication compartments and to chromatin ...
A new method to detect ribonucleic acid (RNA) without needing any complex lab procedures or heating equipment has been developed by researchers at UConn Health. Published in Nature Communications, ...
An EHU study indicates that a drug already approved for use in humans could help to reduce the inflammation associated with celiac disease. The research, conducted by the FunImmune group, shows that ...
理化学研究所(理研)生命医科学研究センタートランスクリプトーム研究チームのアレッサンドロ・ボネッティ客員研究員、ピエロ・カルニンチチームリーダーらの研究チームは、細胞核内のRNAとゲノムDNA(クロマチン[1] )の相互作用をゲノム全体で調べる ...