相同組換えは、DNA分子間の遺伝情報の交換を可能にするDNA修復機構だ。RecAというタンパク質がその過程を取り仕切る様子が、構造解析で明らかにされた。 我々生物の染色体は、常に、ゲノムの完全性が損なわれかねないようなDNA損傷を与える、紫外線や ...
Delivery of therapeutic genes is essential for gene therapy. Adeno-associated viruses (AAVs) are a prime vector for carrying gene cargoes because of their superior gene segmentation flexibility and ...
Delivery of therapeutic genes is essential for gene therapy. Adeno-associated viruses (AAVs) are a prime vector for carrying gene cargoes because of their superior gene segmentation flexibility and ...
A biochemistry research team led by Dr. Andrew H.-J. Wang and Dr. Ting-Fang Wang at the Institute of Biological Chemistry, Academia Sinica(IBCAS), has discovered that the RecA family recombinases ...
A major study published today in the journal Nature has given a new insight into how DNA is repaired – a fundamentally important process in all forms of life and diseases including cancer. Scientists ...
JSTのERATO審良自然免疫プロジェクトとして、審良 静男(大阪大学免疫学フロンティア研究センター拠点長)、石井 健(同微生物病研究所難治感染症対策研究センター准教授)らは、「DNAワクチン」とよばれる新型ワクチンの作用メカニズムを ...