An essential component of living cells, the nucleolus underwent a major evolutionary shift around 300m years ago. Scientists have solved an age-old mystery in biology by discovering a protein found in ...

Gear-obsessed editors choose every product we review. We may earn commission if you buy from a link. Why Trust Us? More than a decade of research shows that the nucleolus—the largest structure in the ...

The nucleolus—a conspicuous but obscure organelle within the cell nucleus—is normally too compact to be studied in detail. Researchers at Case Western Reserve University just learned how to simplify ...

THE nucleolus was first figured in 1781 as a spot in the centre of a round or oval body (the nucleus) in epithelial cells of the eel. Since then it has been described in the nuclei of almost every ...

Biologists discovered that a scaffolding protein called TCOF1 is responsible for the formation of a biomolecular condensate called the fibrillar center, which forms within the cell nucleolus. Inside ...

The size of a cell's nucleolus may reveal how long that cell, or even the organism it belongs to, will live. Over the past few years, researchers have been piecing together an unexpected link between ...

The size of a cell's nucleolus may reveal how long that cell, or even the organism that cell belongs to, will live. Over the past few years, researchers have been piecing together an unexpected link ...

At most, 10 people in the world are known to have BPTA. Five of them participated in the current study, and they were found to share virtually the same mutation in the gene for the HMGB1 protein. It ...

Keeping nucleoli small prevents DNA instability and cellular aging, akin to anti-aging effects like calorie restriction Nucleolar expansion marks a tipping point in aging, acting as a "mortality meter ...