RNA therapeutics target translation rather than DNA, aiming to correct shared protein production errors. By enabling cells to read through premature stop codons, engineered tRNAs could restore ...
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Giant DNA viruses encode their own eukaryote-like translation machinery, researchers discover
In a new study, published in Cell, researchers describe a newfound mechanism for creating proteins in a giant DNA virus, comparable to a mechanism in eukaryotic cells. The finding challenges the dogma ...
九州大学は、極限環境がリボ核酸(RNA)の前生物化学に与える影響を調査し、「アデノシン一リン酸」(AMP)がRNA鎖へ繋がる重合反応を起こす証拠は発見できず、逆に多様な有機化合物へ分解・再編成されることを発見したと発表した。
Researchers develop a single genome-editing strategy to treat multiple disorders caused by nonsense mutations, promising efficient and cost-effective therapies.
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AI breakthrough could dramatically lower the cost of drug development
Three-letter DNA “words” can decide whether a yeast cell cranks out a medicine efficiently or sputters along. The words are ...
Mitochondria possess their own mRNA translation system, mediated by specialized mitoribosomes. Dysregulation of mitochondrial translation disrupts metabolic homeostasis and is linked to various ...
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