How RNA binding selectivity arises from disordered regions

RIKEN researchers have discovered how an enzyme modifies gene expression by targeting certain stretches of messenger RNA ...
eLife

TAD boundary architecture and gene activity are uncoupled

A proposed function of TADs is to contribute to gene regulation by promoting chromatin interactions within a TAD and by suppressing interactions between TADs. Here, we directly probe the ...

Scientists Uncover the Secret Structure Behind “Nature’s Proton Highway”

By freezing a crucial phosphoric acid complex to near absolute zero, scientists uncovered a single, unexpectedly stable structure at the heart of proton transport.

Researchers create new molecule to insert DNA into cells

Getting DNA into a living cell sounds simple, until you remember the cell’s outer membrane acts like a guarded wall. DNA strands carry a negative charge, and they do not cross that wall easily.

Scientists deliver new molecule for getting DNA into cells

Researchers from Tokyo Metropolitan University have created a new molecule which carries DNA into biological cells, to treat or vaccinate against illnesses. Many existing options rely on molecules ...
Drug Target Review

Circular RNA drives 50-fold boost in eye gene therapy

Discover how circular RNA technology enhances gene expression by up to 50-fold in eye treatments, surpassing traditional ...
Open Access Government

Unusual DNA structures and misfolded proteins

Alan Herbert, Founder and President of InsideOutBio, discusses the evolution of biological concepts related to DNA and protein structures ...
Informationsdienst Wissenschaft

A tale of coevolution: Nuclear speckles aid GC-rich RNA processing

Home > Press release: A tale of coevolution: Nuclear speckles ...
News Medical on MSN

Smoking triggers epigenetic damage linked to macular degeneration

Through a series of experiments supported by the National Institutes of Health, Johns Hopkins Medicine (JHM) researchers say they have advanced understanding of how smoking damages the eye and ...

九大、隕石衝突がRNAを合成せずに前駆体を分解してしまうことを発見

九州大学は、極限環境がリボ核酸(RNA)の前生物化学に与える影響を調査し、「アデノシン一リン酸」(AMP)がRNA鎖へ繋がる重合反応を起こす証拠は発見できず、逆に多様な有機化合物へ分解・再編成されることを発見したと発表した。
IFLScience

Genome Of World's Oldest Confirmed Human RNA Virus Reconstructed From 250-Year-Old Lung Tissue

“Our analyses show that the historical [human Rhinovirus] A genome represents an extinct lineage closely related to HRV A19 ...

生命の起源、「RNAワールド仮説」が現実味 自己複製できる45塩基の ...

2019年にスタートした本連載「Innovative Tech」は、世界中の幅広い分野から最先端の研究論文を独自視点で厳選、解説する。執筆は研究論文メディア「Seamless」（シームレス）を主宰し、日課として数多くの論文に目を通す山下氏が担当。イラストや漫画は、同メディア所属のアーティスト・おね氏が手掛けている。X：＠shiropen2 英ケンブリッジ大学などに所属する研究者らがScience誌 ...