In 2021, a technology developed at University of Michigan, called Seq-Scope, revolutionized the ability to map gene activity within intact tissue at ...

A research team at the University of Würzburg has deciphered another aspect of poxviral gene activation. They have revealed a unique viral mechanism: A molecular ring anchors the viral copying machine ...

Researchers identified how the poxvirus protein VITF-3 forms a molecular ring that clamps onto DNA with viral RNA polymerase, bending it by 90 degrees to initiate gene copying.

A research team at the University of Würzburg has deciphered another aspect of poxviral gene activation. The study reveals a ...

A protein’s life is anything but simple. Discover how transcription, translation, folding, modification, and degradation work together to preserve proteome integrity.

Leveraging its integrated "design-synthesis-quality control" system, Creative Biolabs is overcoming bottlenecks in mRNA ...

転写適応は、重要な遺伝子の機能喪失変異を持つ生物個体が、時に生存し、さらに、健全に成長する一因とされているが、そのプロセスはあまり解明されていない。MITのJonathan S. Weissman 教授とHarvard society of fellowsのMohamed El-Brolosy博士が率いる研究チームが今 ...

Researchers at the Weill Institute for Cell and Molecular Biology have uncovered new evidence that two major types of gene-controlling DNA sequences, promoters and enhancers, operate with a shared ...

With big pharma signalling interest in novel RNA-targeted approaches, the term “druggable” is being redefined as technology advances.

This study reports an important and novel finding that TENT5A, an enzyme involved in fine-tuning poly(A) tail length on selected mRNAs, is required for proper enamel mineralization in mice. The ...

New study reveals how cytoplasmic and nuclear functions of USP30-AS1 converge to promote tumor growth Breast cancer progression is increasingly ...