A Cell Death & Disease review synthesizes preclinical evidence that circular RNAs regulate adipose browning and metabolic pathways through microRNA interactions, protein binding, and organelle-linked ...

A secondary stress signaling pathway in the response to optic axon injury is an unexpectedly strong contributor to both neurodegeneration and axon regenerative potential.

Design Therapeutics (NASDAQ:DSGN) outlined progress across three clinical-stage programs and discussed upcoming catalysts during an Oppenheimer healthcare conference presentation led by CEO Pratik ...

A proposed function of TADs is to contribute to gene regulation by promoting chromatin interactions within a TAD and by suppressing interactions between TADs. Here, we directly probe the ...

転写適応は、重要な遺伝子の機能喪失変異を持つ生物個体が、時に生存し、さらに、健全に成長する一因とされているが、そのプロセスはあまり解明されていない。MITのJonathan S. Weissman 教授とHarvard society of fellowsのMohamed El-Brolosy博士が率いる研究チームが今 ...

Changing climate with higher temperatures are increasingly challenging plant growth and productivity, with consequences that cascade from cellular injury to ...

Ribosomes are the components of cells that read RNA and build proteins. Without the ribosome, the chemistry of life would ...

Ribosomes are the components of cells that read RNA and build proteins. Without the ribosome, the chemistry of life would still be catalyzed by raw ...

A protein’s life is anything but simple. Discover how transcription, translation, folding, modification, and degradation work together to preserve proteome integrity.

Leveraging its integrated "design-synthesis-quality control" system, Creative Biolabs is overcoming bottlenecks in mRNA ...

In a new study, published in Cell, researchers describe a newfound mechanism for creating proteins in a giant DNA virus, comparable to a mechanism in eukaryotic cells. The finding challenges the dogma ...

Retrotransposons are pivotal in human genome evolution, driving structural variation and regulatory innovation while influencing health and disease.