For decades, scientists believed a fertilized egg’s DNA began as a shapeless mass, only organizing itself once the embryo switched on its genes. But new research reveals that the genome is already ...

Structural nanomedicine — what helped give us the COVID vaccine — may now be the key to a potent blood cancer treatment that’s had remarkable early results.

C, a tool that helps reveal the genome's structure during the first days of life.

RIKEN researchers have discovered how an enzyme modifies gene expression by targeting certain stretches of messenger RNA ...

Scientists discover hidden DNA scaffolding that forms before genes activate, revealing life’s blueprint is built before it begins.

Human DNA constantly refolds in 3D space, and these looping dynamics regulate gene expression and cell identity.

Cells rely on biomolecular condensates to coordinate essential biological processes without surrounding membranes. These droplet-like ...

A proposed function of TADs is to contribute to gene regulation by promoting chromatin interactions within a TAD and by suppressing interactions between TADs. Here, we directly probe the ...

For decades, scientists viewed the genome of a newly fertilized egg as a structural "blank slate"—a disordered tangle of DNA ...

Researchers at the MRC Laboratory of Medical Sciences (LMS) and Imperial College London have shown for the first time that, before they can start developing into egg and sperm cells, the embryonic ...

Getting DNA into a living cell sounds simple, until you remember the cell’s outer membrane acts like a guarded wall. DNA strands carry a negative charge, and they do not cross that wall easily.

Researchers from Tokyo Metropolitan University have created a new molecule which carries DNA into biological cells, to treat or vaccinate against illnesses.