In 2021, a technology developed at University of Michigan, called Seq-Scope, revolutionized the ability to map gene activity within intact tissue at ...

転写適応は、重要な遺伝子の機能喪失変異を持つ生物個体が、時に生存し、さらに、健全に成長する一因とされているが、そのプロセスはあまり解明されていない。MITのJonathan S. Weissman 教授とHarvard society of fellowsのMohamed El-Brolosy博士が率いる研究チームが今 ...

A protein’s life is anything but simple. Discover how transcription, translation, folding, modification, and degradation work together to preserve proteome integrity.

This study reports an important and novel finding that TENT5A, an enzyme involved in fine-tuning poly(A) tail length on selected mRNAs, is required for proper enamel mineralization in mice. The ...

In a new study, published in Cell, researchers describe a newfound mechanism for creating proteins in a giant DNA virus, comparable to a mechanism in eukaryotic cells. The finding challenges the dogma ...

A research team at the University of Würzburg has deciphered another aspect of poxviral gene activation. They have revealed a unique viral mechanism: A molecular ring anchors the viral copying machine ...

The atomic structural analysis also revealed the role of the so-called capping enzyme. It is stably integrated into the ...

A research team at the University of Würzburg has deciphered another aspect of poxviral gene activation. The study reveals a ...

With big pharma signalling interest in novel RNA-targeted approaches, the term “druggable” is being redefined as technology advances.

Leveraging its integrated "design-synthesis-quality control" system, Creative Biolabs is overcoming bottlenecks in mRNA ...